发明授权
- 专利标题： Dipeptide inhibitors of β-secretase
- 专利标题（中）： β-分泌酶的二肽抑制剂
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申请号： US11075232申请日： 2005-03-08
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公开(公告)号： US07276484B2公开(公告)日： 2007-10-02
- 发明人: Varghese John , Jay Tung , Roy Hom , Ashley Guinn , Lawrence Fang , Andrea Gailunas , Shumeye S. Mamo
- 申请人： Varghese John , Jay Tung , Roy Hom , Ashley Guinn , Lawrence Fang , Andrea Gailunas , Shumeye S. Mamo
- 申请人地址： US CA South San Francisco
- 专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人： Elan Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号： C07K5/06
- IPC分类号： C07K5/06
摘要：
Dipeptide derived inhibitors of the β-secretase enzyme are provided which are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of Aβ peptide in a mammal. The compounds of the invention provide useful methods of treatment by administration of these inhibitors to reduce Aβ peptide formation and in pharmaceutical compositions.
公开/授权文献
- US20050182138A1 Dipeptide inhibitors of beta-secretase 公开/授权日：2005-08-18
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