One embodiment of the present invention may include a programmable gain amplifier comprising an input multiplexer operative to sequentially select input signals for amplification. The input signals may be chosen from a plurality of input signals based on a selection signal. The programmable gain amplifier may include at least one amplifier gain stage operative to apply a variable gain amount to a selected input signal. The programmable gain amplifier may further include a gain mapping component that controls the variable gain amount for each of the selected input signals.