发明授权
- 专利标题： Amidino compounds useful as nitric oxide synthase inhibitors
- 专利标题（中）： 可用作一氧化氮合酶抑制剂的脒基化合物
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申请号： US11032650申请日： 2005-01-10
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公开(公告)号： US07196118B2公开(公告)日： 2007-03-27
- 发明人: Ronald Keith Webber , Richard C. Durley , Alok K. Awasthi , Arija A. Bergmanis , Kam F. Fok , Scott S. Ganser , Timothy J. Hagen , E. Ann Hallinan , Donald W. Hansen, Jr. , Brian S. Hickory , Pamela T. Manning , Michael Mao , Alan E. Moormann , Barnett S. Pitzele , Michelle A. Promo , Richard R. Schartman , Jeffrey A. Scholten , Jeffrey S. Snyder , Mihaly V. Toth , Mahima Trivedi , Sofya Tsymbalov , Foe Siong Tjoeng
- 申请人： Ronald Keith Webber , Richard C. Durley , Alok K. Awasthi , Arija A. Bergmanis , Kam F. Fok , Scott S. Ganser , Timothy J. Hagen , E. Ann Hallinan , Donald W. Hansen, Jr. , Brian S. Hickory , Pamela T. Manning , Michael Mao , Alan E. Moormann , Barnett S. Pitzele , Michelle A. Promo , Richard R. Schartman , Jeffrey A. Scholten , Jeffrey S. Snyder , Mihaly V. Toth , Mahima Trivedi , Sofya Tsymbalov , Foe Siong Tjoeng
- 申请人地址： US MO St. Louis
- 专利权人： Pharmacia Corporation
- 当前专利权人： Pharmacia Corporation
- 当前专利权人地址： US MO St. Louis
- 代理机构： Pharmacia Corporation
- 主分类号： A61K31/195
- IPC分类号： A61K31/195
摘要：
The present invention relates to amidino compounds and salts and prodrugs thereof. In another embodiment the present invention also provides a use of the present compounds in therapy, particular as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods of making the amidino compounds.
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