发明授权
- 专利标题: High affinity RNA ligands of basic fibroblast growth factor
- 专利标题(中): 碱性成纤维细胞生长因子的高亲和力RNA配体
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申请号: US10885403申请日: 2004-07-06
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公开(公告)号: US07196069B2公开(公告)日: 2007-03-27
- 发明人: Nebojsa Janjic , Larry Gold
- 申请人: Nebojsa Janjic , Larry Gold
- 申请人地址: US CA Forster City
- 专利权人: Gilead Sciences, Inc.
- 当前专利权人: Gilead Sciences, Inc.
- 当前专利权人地址: US CA Forster City
- 代理机构: Swanson & Bratschun, L.L.C.
- 主分类号: A01N43/04
- IPC分类号: A01N43/04 ; A61K31/70 ; C07H21/04
摘要:
Methods are described for the identification and preparation of nucleic acid ligand solutions to basic fibroblast growth factor (bFGF). Included in the invention are nucleic acid ligands to bFGF which are inhibitors of bFGF and 2′-amino-modified RNA ligands to bFGF.
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