发明授权
- 专利标题： Neural stem cells and use thereof for brain tumor therapy
- 专利标题（中）： 神经干细胞及其在脑肿瘤治疗中的应用
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申请号： US09795675申请日： 2001-02-28
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公开(公告)号： US07186409B2公开(公告)日： 2007-03-06
- 发明人: Evan Y. Snyder , Xandra O. Breakefield , Karen S. Aboody , Ulrich Herrlinger , William P. Lynch
- 申请人： Evan Y. Snyder , Xandra O. Breakefield , Karen S. Aboody , Ulrich Herrlinger , William P. Lynch
- 申请人地址： US MA Boston US MA Charlestown US OH Rootstown
- 专利权人： The Children's Medical Center Corporation,The General Hospital Corporation,Northeastern Ohio Universities College of Medicine
- 当前专利权人： The Children's Medical Center Corporation,The General Hospital Corporation,Northeastern Ohio Universities College of Medicine
- 当前专利权人地址： US MA Boston US MA Charlestown US OH Rootstown
- 代理机构： Nixon Peabody LLP
- 主分类号： A01N63/00
- IPC分类号： A01N63/00 ; A61K48/00 ; C12N5/08 ; C12N15/63
摘要：
The present invention is based upon a surprising finding that stem cells, more particularly neural stem cells, can migrate throughout a brain tumor and track metastatic brain tumor cells. The invention provides a method for treating brain tumors by administering genetically engineered neural stem cells in an individual affected by brain tumors. The invention also provides a method of preparing genetically engineered neural stem cells and a composition comprising genetically engineered neural stem cells in a pharmaceutically acceptable carrier.
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