- 专利标题: Delivery of diazepam through an inhalation route
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申请号: US10792013申请日: 2004-03-03
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公开(公告)号: US07087218B2公开(公告)日: 2006-08-08
- 发明人: Joshua D. Rabinowitz , Alejandro C. Zaffaroni
- 申请人: Joshua D. Rabinowitz , Alejandro C. Zaffaroni
- 申请人地址: US CA Palo Alta
- 专利权人: Alexza Pharmaceuticals, Inc.
- 当前专利权人: Alexza Pharmaceuticals, Inc.
- 当前专利权人地址: US CA Palo Alta
- 代理机构: Swanson & Bratschun LLC
- 代理商 William L. Leschensky
- 主分类号: A61K9/12
- IPC分类号: A61K9/12 ; A61K9/14 ; A61M15/00
摘要:
The present invention relates to the delivery of compounds for the treatment of anxiety disorders and symptoms of such disorders through an inhalation route. Specifically, it relates to aerosols containing diazepam that are used in inhalation therapy. In a method aspect of the present invention, diazepam is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of diazepam on a solid support to form a vapor; and, b) passing air through the heated vapor to produce aerosol particles having less than 5% drug degradation products. In a kit aspect of the present invention, a kit for delivering diazepam through an inhalation route is provided which comprises: a) a thin coating of a diazepam composition; and, b) a device for dispending said thin coating as a condensation aerosol.
公开/授权文献
- US20040170571A1 Delivery of diazepam through an inhalation route 公开/授权日:2004-09-02
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