发明授权
US07041296B1 Methods of treating inflammatory bowel disease using cholera toxin B subunit
有权
使用霍乱毒素B亚基治疗炎症性肠病的方法
- 专利标题： Methods of treating inflammatory bowel disease using cholera toxin B subunit
- 专利标题（中）： 使用霍乱毒素B亚基治疗炎症性肠病的方法
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申请号： US10129907申请日： 2000-11-09
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公开(公告)号： US07041296B1公开(公告)日： 2006-05-09
- 发明人: Warren Stober , Ivan J. Fuss , Brian L. Kelsall , Monica Boirivant
- 申请人： Warren Stober , Ivan J. Fuss , Brian L. Kelsall , Monica Boirivant
- 申请人地址： US DC Washington
- 专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Needle & Rosenberg, P.C.
- 国际申请： PCT/US00/30837 WO 20001109
- 国际公布： WO01/34175 WO 20010517
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
The present invention provides a method of treating or preventing inflammation in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B. The present invention also provides a method of decreasing the activity of interferon gamma in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B. Further provided is a method of decreasing the activity of IL-12 in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B. Additionally, the present invention provides a method of treating or preventing a Th1 T-cell mediated autoimmune disorder in a subject, comprising administering to the subject an effective amount of cholera toxin subunit B.
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