发明授权
US06919455B2 Purine derivative dihydrate, drugs containing the same as the active ingredient and intermediate in the production thereof
失效
嘌呤衍生物二水合物，含有与活性成分相同的药物及其生产中的中间体
- 专利标题： Purine derivative dihydrate, drugs containing the same as the active ingredient and intermediate in the production thereof
- 专利标题（中）： 嘌呤衍生物二水合物，含有与活性成分相同的药物及其生产中的中间体
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申请号： US10631795申请日： 2003-08-01
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公开(公告)号： US06919455B2公开(公告)日： 2005-07-19
- 发明人: Kouichi Sekiya , Akihiro Takemiya
- 申请人： Kouichi Sekiya , Akihiro Takemiya
- 申请人地址： JP Tokyo
- 专利权人： Mitsubishi Chemical Corporation
- 当前专利权人： Mitsubishi Chemical Corporation
- 当前专利权人地址： JP Tokyo
- 代理机构： Greenblum & Bernstein, P.L.C.
- 优先权： JP11-129499 19990511
- 主分类号： A61K31/52
- IPC分类号： A61K31/52 ; A61P11/00 ; A61P11/06 ; A61P29/00 ; A61P43/00 ; C07D473/00 ; C07D473/28 ; C07D473/36 ; C07D473/40 ; C07F9/6561
摘要：
A compound represented by the following formula (I), or a salt thereof: where X is a halogen atom or a group represented by —S—(CH2)n—A, —SO—(CH2)m—B, —SO2—(CH2)m —B, —OSO2—(CH2)m—B, —OCO—(CH2)m—B or —OPO(OR)—(CH2)m—B, wherein n represents an integer of 0-4, A represents an optionally substituted aromatic hydrocarbon group or an optionally substituted heterocyclic residue having 1 to 4 hetero atoms selected from an oxygen atom, sulfur atom and nitrogen atom and having 5 to 10 ring-constituent atoms, m represents an integer of 0-4, B represents an optionally substituted alkyl group, an optionally substituted aromatic hydrocarbon group or an optionally substituted heterocyclic residue having 1 to 4 hetero atoms selected from an oxygen atom, sulfur atom and nitrogen atom and having 5 to 10 ring-constituent atoms, and R represents an optionally substituted alkyl group.
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