发明授权
US06770625B2 Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
有权
降钙素药物 - 低聚物共轭物的药物组合物及其治疗疾病的方法
- 专利标题: Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
- 专利标题(中): 降钙素药物 - 低聚物共轭物的药物组合物及其治疗疾病的方法
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申请号: US10235284申请日: 2002-09-05
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公开(公告)号: US06770625B2公开(公告)日: 2004-08-03
- 发明人: Richard Soltero , Nnochiri N. Ekwuribe , Foyeke Opawale , Bruce Rehlaender , Anthony Hickey , Li Li Bovet
- 申请人: Richard Soltero , Nnochiri N. Ekwuribe , Foyeke Opawale , Bruce Rehlaender , Anthony Hickey , Li Li Bovet
- 主分类号: A61K3802
- IPC分类号: A61K3802
摘要:
Pharmaceutical compositions that include a drug-oligomer conjugate, a fatty acid component, and a bile salt component are described. The drug is covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component are present in a weight-to-weight ratio of between 1:5 and 5:1. Methods of treating diseases in a subject in need of such treatment using such pharmaceutical compositions are also provided, as are methods of providing such pharmaceutical compositions.
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