发明授权
- 专利标题： Npyy5 antagonists
- 专利标题（中）： Npyy5拮抗剂
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申请号： US10111981申请日： 2002-05-01
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公开(公告)号： US06699891B1公开(公告)日： 2004-03-02
- 发明人: Yasuyuki Kawanishi , Hideyuki Takenaka , Kohji Hanasaki , Tetsuo Okada
- 申请人： Yasuyuki Kawanishi , Hideyuki Takenaka , Kohji Hanasaki , Tetsuo Okada
- 优先权： JP11/336469 19991126; JP11/353786 19991214
- 主分类号： A61K3144
- IPC分类号： A61K3144
摘要：
The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof.
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