发明授权
- 专利标题： Compounds derived from an amine nucleus and pharmaceutical compositions comprising same
- 专利标题（中）： 衍生自胺核的化合物和包含其的药物组合物
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申请号： US09997963申请日： 2001-11-29
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公开(公告)号： US06596747B2公开(公告)日： 2003-07-22
- 发明人: Chunjian Liu , T. G. Murali Dhar , Henry H. Gu , Edwin J. Iwanowicz , Katerina Leftheris , William J. Pitts , Timothy F. Herpin , Gregory S. Bisacchi
- 申请人： Chunjian Liu , T. G. Murali Dhar , Henry H. Gu , Edwin J. Iwanowicz , Katerina Leftheris , William J. Pitts , Timothy F. Herpin , Gregory S. Bisacchi
- 主分类号： A61K3142
- IPC分类号： A61K3142
摘要：
Compounds having the formula (I), are effective as inhibitors of IMPDH enzyme and/or serine protease Factor VIIa, wherein B is a monocyclic or bicyclic carbocyclic or heterocyclic ring, D is a monocyclic or bicyclic carbocyclic or heterocyclic ring except when A is a heterocyclic ring, then D is a heterocyclic ring system, R is hydrogen or C1-4alkyl, and A, R1, R2 and R4 are as defined in the specification.
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