发明授权
US06492550B2 Alpha-substituted thio, -oxo trifluoromethylketones as phospholipase inhibitors
有权
α-取代的硫代氧基三氟甲基酮作为磷脂酶抑制剂
- 专利标题: Alpha-substituted thio, -oxo trifluoromethylketones as phospholipase inhibitors
- 专利标题(中): α-取代的硫代氧基三氟甲基酮作为磷脂酶抑制剂
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申请号: US09779411申请日: 2001-02-08
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公开(公告)号: US06492550B2公开(公告)日: 2002-12-10
- 发明人: Jacques Banville , Serge Plamondon , Yonghua Gai , Neelakantan Balasubramanian
- 申请人: Jacques Banville , Serge Plamondon , Yonghua Gai , Neelakantan Balasubramanian
- 主分类号: C07C59147
- IPC分类号: C07C59147
摘要:
Inhibitors of the cytosolic phospholypase A2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula where X, Z, X1, R1, R2, Ra and Rb are as defined in the specification.
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