Invention Grant
- Patent Title: Method for synthesizing C-glycosides of ulosonic acids
- Patent Title (中): 尿苷酸的C-糖苷的合成方法
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Application No.: US09142937Application Date: 1998-11-17
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Publication No.: US06376662B1Publication Date: 2002-04-23
- Inventor: Robert J. Linhardt , Iontcho R. Vlahov
- Applicant: Robert J. Linhardt , Iontcho R. Vlahov
- Main IPC: C07H704
- IPC: C07H704
Abstract:
A method for synthesizing C-glycosides of ulosonic acids such as Neu5Ac, by which diastereocontrolled synthesis of &agr;-C-glycosides of ulosonic acids is attained is disclosed. In the method of the present invention, an ulosonic acid sulfone or phosphite is reacted with an aldehyde or ketone compound in the presence of a lanthanide metal halide.
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