Invention Grant
US06350589B1 Compositions of highly-purified natural mixtures of type I interferon derived from leukocytes and methods
失效
来自白细胞的I型干扰素的高度纯化天然混合物的组合物和方法
- Patent Title: Compositions of highly-purified natural mixtures of type I interferon derived from leukocytes and methods
- Patent Title (中): 来自白细胞的I型干扰素的高度纯化天然混合物的组合物和方法
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Application No.: US09224895Application Date: 1998-12-31
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Publication No.: US06350589B1Publication Date: 2002-02-26
- Inventor: Joseph P. Morris , Duy Nguyen , James Kappelman , Michael D. Potter , Mead M. McCabe , Reza Ziai , Stephen B. Feldman , Hipolito Hartman
- Applicant: Joseph P. Morris , Duy Nguyen , James Kappelman , Michael D. Potter , Mead M. McCabe , Reza Ziai , Stephen B. Feldman , Hipolito Hartman
- Main IPC: C12P100
- IPC: C12P100
Abstract:
This invention relates to methods for isolating highly-purified mixtures of natural type I interferons from white blood cells. The invention also relates to highly-purified mixtures of natural type I interferons which resemble natural type I interferon in that it includes 9 subtypes, i.e., alpha-1, alpha-2, alpha-5, alpha-7, alpha-8, alpha-10, alpha-14, alpha-21 and omega, giving rise to possibly 20 molecular species, including alpha-1a, alpha-1new, alpha-2a, alpha-2b, alpha-2c, alpha-5, alpha-5LG, alpha-7, alpha-8a, alpha-8c, alpha-10a, alpha-14a, alpha14-b, alpha 14-c, alpha-14LG, alpha-21a, alpha-21b, alpha-21c, omega and omega LG.
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