Invention Grant
US06287834B1 Characterization and use of an isolated uridine diphospho-glucuronosyltransferase
失效
分离的尿苷二磷酸 - 葡萄糖醛酸基转移酶的表征和使用
- Patent Title: Characterization and use of an isolated uridine diphospho-glucuronosyltransferase
- Patent Title (中): 分离的尿苷二磷酸 - 葡萄糖醛酸基转移酶的表征和使用
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Application No.: US09180852Application Date: 1999-02-08
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Publication No.: US06287834B1Publication Date: 2001-09-11
- Inventor: Alain Belanger , Dean W. Hum , Martin Beaulieu , Eric Levesque
- Applicant: Alain Belanger , Dean W. Hum , Martin Beaulieu , Eric Levesque
- Main IPC: C12P2106
- IPC: C12P2106
Abstract:
A uridine diphospho-glucuronosyltransferase (UGTB217) is provided. Methods of producing the enzyme and using the enzyme to identify potential compounds which inhibit or alter the activity of the enzyme are described. In addition, methods of using antibodies to localize the protein, or using the gene sequence or portions thereof for probes or using the gene sequence to produce expression-disrupting sense or antisense DNA fragments thereof, or antisense RNA, are provided.
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