Invention Grant
- Patent Title: Radiopharmaceutical compositions that include an inclusion complex of a cyclodextrin and a radio-halogenated fatty acid
- Patent Title (中): 包括环糊精和放射性卤代脂肪酸的包合物的放射性药物组合物
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Application No.: US836196Application Date: 1997-05-14
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Publication No.: US5993776APublication Date: 1999-11-30
- Inventor: Roberto Pasqualini , Bruno Perly , Laurent Mauclaire , Florence Djedaini-Pilard , Yves Michel
- Applicant: Roberto Pasqualini , Bruno Perly , Laurent Mauclaire , Florence Djedaini-Pilard , Yves Michel
- Applicant Address: FRX Saclay
- Assignee: CIS bio International
- Current Assignee: CIS bio International
- Current Assignee Address: FRX Saclay
- Priority: FRX9413609 19941114
- Main IPC: A61K47/48
- IPC: A61K47/48 ; A61K51/12 ; A61K51/00 ; A61M36/14
Abstract:
The invention relates to radio-pharmaceutical compositions that include an inclusion complex of a cyclodextrin and a radio-halogenated fatty acid.These complexes include a cyclodextrin such as .beta.-cyclodextrin, .gamma.-cyclodextrin and their derivatives, and a radio-halogenated fatty acid, in particular a fatty acid labelled with radioactive iodine such as 16-iodo 3-methyl hexadecanoic acid suitable for the examination of the myocardium by scintigraphy.The cyclodextrin allows the fatty acid to dissolve in aqueous solution without any addition of human blood albumin, while further improving the biodistribution of the fatty acid and its stability to heat.
Public/Granted literature
- USD299060S Blood pressure meter Public/Granted day:1988-12-20
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