发明授权
US5976541A Potent peptide for stimulation of cytotoxic T lymphocytes specific for
the HIV-1 envelope
失效
用于刺激特异于HIV-1信封的细胞毒性T淋巴细胞的强力肽
- 专利标题： Potent peptide for stimulation of cytotoxic T lymphocytes specific for the HIV-1 envelope
- 专利标题（中）： 用于刺激特异于HIV-1信封的细胞毒性T淋巴细胞的强力肽
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申请号： US847311申请日： 1992-03-06
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公开(公告)号： US5976541A公开(公告)日： 1999-11-02
- 发明人: Jay A. Berzofsky , Toshiyuki Taskeshita , Mutsunori Shirai , C. David Pendleton , Steven Kozlowski , David H. Margulies
- 申请人： Jay A. Berzofsky , Toshiyuki Taskeshita , Mutsunori Shirai , C. David Pendleton , Steven Kozlowski , David H. Margulies
- 申请人地址： DC Washington
- 专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址： DC Washington
- 主分类号： A61K38/03
- IPC分类号： A61K38/03 ; A61K38/55 ; A61K39/00 ; A61P31/18 ; C07K7/06 ; C07K7/08 ; C07K14/16 ; C12N15/48 ; A61K39/21 ; A61K39/12 ; A61K39/38 ; C12N15/00
摘要：
Peptides having high activity in the eliciting of a cytotoxic T lymphocyte response to the HIV-1 envelope glycoprotein gpl60 are described. The activation of 12-15 residue peptides by proteolytic degradation to shorter peptides is shown as are general techniques for characterizing such activation processes.
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