Invention Grant
- Patent Title: Peptide derivatives
- Patent Title (中): 肽衍生物
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Application No.: US272704Application Date: 1994-07-07
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Publication No.: US5656721APublication Date: 1997-08-12
- Inventor: Rainer Albert , Wilfried Bauer , Francois Cardinaux , Monika Mergler , Janos Pless , Walter Prikoszovich
- Applicant: Rainer Albert , Wilfried Bauer , Francois Cardinaux , Monika Mergler , Janos Pless , Walter Prikoszovich
- Applicant Address: CHX Basel
- Assignee: Sandoz Ltd.
- Current Assignee: Sandoz Ltd.
- Current Assignee Address: CHX Basel
- Priority: DEX3634797.3 19861013; DEX3634826.0 19861013; DEX3634825.2 19861013; DEX3712626.1 19870414; CHX03153/87 19870817
- Main IPC: A61K31/70
- IPC: A61K31/70 ; A61K38/00 ; A61K38/04 ; A61K38/22 ; A61K38/23 ; A61K38/27 ; A61K38/43 ; A61K38/55 ; A61P1/00 ; A61P1/04 ; A61P3/08 ; A61P5/00 ; A61P9/00 ; C07K1/00 ; C07K1/02 ; C07K1/107 ; C07K1/113 ; C07K1/12 ; C07K7/06 ; C07K7/16 ; C07K9/00 ; C07K14/00 ; C07K14/52 ; C07K14/575 ; C07K14/585 ; C07K14/60 ; C07K14/62 ; C07K14/655 ; C07K17/08 ; A61K38/31
Abstract:
The present invention provides a sugar derivative of a biologically active peptide, which derivative has a prolonged duration of action when compared to the non-sugar modified peptide, and contains at least on one of the amino acid units a sugar residue which is attached to an amino group thereof by a coupling other than a direct N-glycosidic bond, and additionally, when it is a condensation product of a carboxyl group containing sugar and a peptide with less than 8 amino acid units, by a coupling other than a direct amide bond.
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