Invention Grant
- Patent Title: Antibodies with altered effector functions
- Patent Title (中): 具有改变的效应子功能的抗体
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Application No.: US479752Application Date: 1995-06-07
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Publication No.: US5624821APublication Date: 1997-04-29
- Inventor: Gregory P. Winter , Alexander R. Duncan , Dennis R. Burton
- Applicant: Gregory P. Winter , Alexander R. Duncan , Dennis R. Burton
- Applicant Address: CA Menlo Park
- Assignee: Scotgen Biopharmaceuticals Incorporated
- Current Assignee: Scotgen Biopharmaceuticals Incorporated
- Current Assignee Address: CA Menlo Park
- Priority: GBX8706425 19870318; GBX8718897 19870810; GBX8728042 19871201; WOXPCT/GB88/00211 19880318
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K14/00 ; C07K14/435 ; C07K16/00 ; C07K19/00 ; C12N15/09 ; C12N15/20 ; C12P21/00 ; C12P21/08 ; C12N15/00 ; C12N1/20
Abstract:
An antibody with an altered function, e.g. altered affinity for an effector ligand such as Fc receptor (FcR) on a cell or the C1 component of complement is produced by replacing at least one amino acid residue in the constant portion of the antibody with a different residue.
Public/Granted literature
- USD327559S Vehicle trunk loading/unloading ramp Public/Granted day:1992-06-30
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