发明授权
US5602248A Process for preparation of
9.alpha.-chloro-11.beta.-formyloxypregna-3,20-diones
失效
制备9α-chlor-11β-甲氧基孕激素-3,20-二氢睾酮的方法
- 专利标题： Process for preparation of 9.alpha.-chloro-11.beta.-formyloxypregna-3,20-diones
- 专利标题（中）： 制备9α-chlor-11β-甲氧基孕激素-3,20-二氢睾酮的方法
-
申请号： US405110申请日： 1995-03-16
-
公开(公告)号： US5602248A公开(公告)日： 1997-02-11
- 发明人: Richard W. Draper , Eugene J. Vater
- 申请人： Richard W. Draper , Eugene J. Vater
- 申请人地址： NJ Kenilworth
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 当前专利权人地址： NJ Kenilworth
- 主分类号： C07J7/00
- IPC分类号： C07J7/00 ; C07J17/00 ; C07J75/00
摘要：
Disclosed is a process for producing a compound of the formula: ##STR1## by reacting a compound of the formula: ##STR2## with: (1) a chlorinating reagent selected from an N-chloroimide or an N-chloroamide; (2) an anhydrous strong acid selected from orthophosphoric acid, alkylsulfonic acids, fluoroalkylsulfonic acids or arylsulfonic acids; and (3) anhydrous dimethyl formamide; at a temperature within the range of about -78.degree. to about 0.degree. C., under anhydrous conditions under an inert atmosphere.
公开/授权文献
信息查询
