发明授权
- 专利标题: Benzophenones having an antifungal activity
- 专利标题(中): 具有抗真菌活性的二苯甲酮
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申请号: US131880申请日: 1993-10-05
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公开(公告)号: US5464836A公开(公告)日: 1995-11-07
- 发明人: Giovanni Camaggi , Lucio Filippini , Marilena Gusmeroli , Raul Riva , Carlo Garavaglia , Luigi Mirenna
- 申请人: Giovanni Camaggi , Lucio Filippini , Marilena Gusmeroli , Raul Riva , Carlo Garavaglia , Luigi Mirenna
- 申请人地址: ITX Rome
- 专利权人: Ministero dell'Universita` e della Ricerca Scientifica e Tecnologica
- 当前专利权人: Ministero dell'Universita` e della Ricerca Scientifica e Tecnologica
- 当前专利权人地址: ITX Rome
- 优先权: ITXMI91A1812 19910701
- 主分类号: A01N37/44
- IPC分类号: A01N37/44 ; A01N35/04 ; A01N43/84 ; C07C45/51 ; C07C49/86 ; C07C217/22 ; C07C225/06 ; C07C225/16 ; C07C233/69 ; C07D265/30 ; C07D279/12 ; C07D295/092 ; C07D295/112 ; A61K31/535 ; C07C211/27
摘要:
A description follows of benzophenones having an antifungal activity and responding to the general formula (I): ##STR1## wherein: R.sub.1 and R.sub.2, the same or different, represent C.sub.1 -C.sub.6 alkyl groups, C.sub.7 -C.sub.10 arylalkyl groups; or R.sub.1 and R.sub.2, considered jointly with N, represent a C.sub.3 -C.sub.8 heterocyclic group or a C.sub.2 -C.sub.7 heterocyclic group containing a second hetero-atom selected from O and S, said heterocyclic groups being optionally subsituted with one or more C.sub.1 -C.sub.4 alkyl groups;R.sub.3 and R.sub.4, the same or different, represent H atoms, C.sub.1 -C.sub.3 alkyl groups;K represents an oxygen atom or methylene;A represents a benzene group, optionally sustituted with one or more halogen atoms, C.sub.1 -C.sub.4 alkyl or haloalkyl groups, C.sub.1 -C.sub.4 alkoxylics, C.sub.1 -C.sub.4 haloalkoxylics;Y represents a C.sub.6 -C.sub.10 aryl group; said group may be optionally substituted with one or more halogen atomos, C.sub.1 -C.sub.4 alkyl or haloalkyl groups, C.sub.1 -C.sub.4 alkoxylics, C.sub.1 -C.sub.4 haloalkoxylics.
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