A universal pipe support and hanger system comprising a single support member of generally I-shaped cross-section elongated in a first direction between a proximate end and a distal end, and comprising an elongated central web integrally connected with midpoints of first and second flanges extending substantially at right angles to the web, in a second direction. The proximate end has an L-shaped flange for mounting the single support member against a flat surface or a DMV in at least two orthogonal directions. Upper and lower edges of each flange comprise v-shaped cradles to support pipes extending in a third direction. A plurality of septa extend between opposed inner surfaces of said first and second flanges, on either side of the web, so as to define compartments. A plurality of mounting devices, including a novel preloaded small pipe strap, are adapted to frictionally engage a pair of septa and remain slightly in the web when mounting pipes of varying outer diameters, against one or more of said v-shaped cradles.