发明授权
- 专利标题: Indan derivatives and pharmaceutical preparation thereof
- 专利标题(中): Indan衍生物及其药物制剂
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申请号: US271324申请日: 1988-11-15
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公开(公告)号: US5030652A公开(公告)日: 1991-07-09
- 发明人: Takeo Iwakuma , Harumichi Kohno , Yasuhiko Sasaki , Katsuo Ikezawa , Akio Odawara
- 申请人: Takeo Iwakuma , Harumichi Kohno , Yasuhiko Sasaki , Katsuo Ikezawa , Akio Odawara
- 申请人地址: JPX Osaka
- 专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX62-290957 19871118; JPX63-152642 19880621; JPX63-152643 19880621
- 主分类号: C07C233/52
- IPC分类号: C07C233/52 ; C07C311/20 ; C07C311/29 ; C07D257/06 ; C07D333/34 ; C07D333/36
摘要:
Indan derivatives of the formula: ##STR1## wherein R.sup.1 is substituted or unsubstituted phenyl, naphthyl or sulfur-containing heterocyclic group, and R.sup.2 is hydroxy-methyl or a group of the formula: ##STR2## wherein R.sup.3 is hydrogen atom or lower alkyl and R.sup.4 is cycloalkyl, lower alkoxycarbonyl-phenyl, carboxy-phenyl, nitrogen-containing heterocyclic group, lower alkyl, or lower alkyl having a substituent selected from lower alkoxycarbonyl, carboxy, lower alkoxycarbonyl-phenyl, carboxy-phenyl, lower alkoxycarbonyl-cycloalkyl and carboxy-cycloalkyl, or a pharmaceutically acceptable salt thereof, which are useful as a platelet aggregation-inhibiting agent and as an agent for the treatment, amelioration and/or prophylaxis of a variety of thrombosis or embolism, coronary and cerebral vascular smooth muscle vellication, asthma, and the like, processes for the preparation thereof, and pharmaceutical composition containing said compound as an active ingredient.
公开/授权文献
- US5552035A Zeolite aggregates and catalysts 公开/授权日:1996-09-03
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