发明授权
- 专利标题: Irradiation of blood products
- 专利标题(中): 血液制品的照射
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申请号: US900217申请日: 1986-08-26
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公开(公告)号: US4726949A公开(公告)日: 1988-02-23
- 发明人: Jeffrey E. Miripol , Arnold Bilstad , John Foley , Dean Glash
- 申请人: Jeffrey E. Miripol , Arnold Bilstad , John Foley , Dean Glash
- 申请人地址: IL Deerfield
- 专利权人: Baxter Travenol Laboratories, Inc.
- 当前专利权人: Baxter Travenol Laboratories, Inc.
- 当前专利权人地址: IL Deerfield
- 主分类号: A61K35/14
- IPC分类号: A61K35/14 ; A61M1/36
摘要:
A thin film of white blood cells is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 15 milliwatts per square cm. At such a radiation intensity it is not necessary to agitate the thin film of white blood cells to accomplish the purposes of this invention. The white blood cells so processed substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation.
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