发明授权
US4622405A 1,2,3,3a,8,8a-hexahydro-indeno[1,2-c]pyrroles useful in the treatment of
hypertension
失效
1,2,3,3a,8,8a-六氢 - 茚并[1,2-c]吡咯，用于治疗高血压
- 专利标题： 1,2,3,3a,8,8a-hexahydro-indeno[1,2-c]pyrroles useful in the treatment of hypertension
- 专利标题（中）： 1,2,3,3a,8,8a-六氢 - 茚并[1,2-c]吡咯，用于治疗高血压
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申请号： US695520申请日： 1985-01-28
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公开(公告)号： US4622405A公开(公告)日： 1986-11-11
- 发明人: John F. DeBernardis , Martin Winn
- 申请人： John F. DeBernardis , Martin Winn
- 申请人地址： IL North Chicago
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： IL North Chicago
- 主分类号： C07C62/34
- IPC分类号： C07C62/34 ; C07D209/94 ; C07D209/56 ; A61K31/40
摘要：
Disclosed herein are 1,2,3,3a,8,8a-hexahydro-indeno[1,2-c]pyrroles represented by the formula ##STR1## wherein R.sub.1 is hydrogen, loweralkyl of 1 to 5 carbon atoms, arylalkyl, loweracyl or benzoalkylenedioxy; R.sub.2 and R.sub.3 may be the same or different and are hydroxy, loweralkoxy, halo, thiomethyl, loweracyl, NR.sub.4 R.sub.5, NHSO.sub.2 R.sub.6 or arylalkoxy or R.sub.2 and R.sub.3 taken together may form a methylenedioxy or ethylenedioxy bridge; R.sub.4 and R.sub.5 may be the same or different and are hydrogen, loweralkyl of 1 to 2 carbon atoms or loweracyl; and R.sub.6 is hydrogen or loweralkyl of 1 to 2 carbon atoms.
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