发明授权
US4374979A Regiospecific synthesis of anthracyclinone compounds such as
daunomycinone
失效
蒽环类化合物如道诺霉素的区域特异性合成
- 专利标题： Regiospecific synthesis of anthracyclinone compounds such as daunomycinone
- 专利标题（中）： 蒽环类化合物如道诺霉素的区域特异性合成
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申请号： US258193申请日： 1981-04-27
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公开(公告)号： US4374979A公开(公告)日： 1983-02-22
- 发明人: Lester A. Mitscher
- 申请人： Lester A. Mitscher
- 申请人地址： KS Lawrence
- 专利权人： The University of Kansas Endowment Association
- 当前专利权人： The University of Kansas Endowment Association
- 当前专利权人地址： KS Lawrence
- 主分类号： C07C43/225
- IPC分类号： C07C43/225 ; C07C43/23 ; C07C45/46 ; C07C45/58 ; C07C45/59 ; C07C45/63 ; C07C205/57 ; C07D303/22 ; C07H15/24 ; C07C49/72 ; C07C49/74 ; C07C49/84
摘要：
A regiospecific synthesis for anthracyclinones asymmetric is disclosed. The synthesis is based upon a regiospecific bromination of the C-7 position of the .alpha.-tetralone which after transposing the keto group to the .beta.-position and reaction with an organo-lithium compound is condensed with a phthalate ester.
公开/授权文献
- US5468577A Photomask having patterns to reduce power of a stepper 公开/授权日：1995-11-21
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