发明授权
- 专利标题： Compounds with ergoline skeleton
- 专利标题（中）： 麦角骨骨架化合物
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申请号： US579979申请日： 1975-05-22
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公开(公告)号： US4005089A公开(公告)日： 1977-01-25
- 发明人: Erzsebet Mago nee Karacsony , Jozsef Borsi , Endre Csanyi , Katalin Pik , Lajos Wolf
- 申请人： Erzsebet Mago nee Karacsony , Jozsef Borsi , Endre Csanyi , Katalin Pik , Lajos Wolf
- 申请人地址： HU Budapest
- 专利权人： Richter Gedeon Vegyeszeti Gyar Rt.
- 当前专利权人： Richter Gedeon Vegyeszeti Gyar Rt.
- 当前专利权人地址： HU Budapest
- 优先权： HUG01272 19740528
- 主分类号： A61K31/48
- IPC分类号： A61K31/48 ; A61P25/24 ; A61P25/26 ; A61P43/00 ; C07D457/02 ; C07D457/06
摘要：
New compounds of the general formula (I) ##STR1## wherein R stands for hydrogen or methyl group,x y stands for a group of the formula ##STR2## and R.sub.1 stands for a group of the formula (III), (IV) or (V) ##STR3## wherein n is an integer from 4 to 10, ARE PREPARED BY ACYLATING A COMPOUND OF THE GENERAL FORMULA (II), ##STR4## wherein R and x y each have the same meanings as defined above, and R.sub.2 stands for a group of the formula (VI), (VII) or (VIII), ##STR5## with a C.sub.6-12 carboxylic acid or a C.sub.6-12 carboxylic acid halide. The new compounds of the general formula (I) and their acid addition salts can be used as antidepressants and antiserotonine agents with prolonged effects.
公开/授权文献
- US5636616A Fuel supply apparatus for an internal combustion engine 公开/授权日：1997-06-10
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