发明公开
- 专利标题： AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
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申请号： US18245167申请日： 2021-09-21
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公开(公告)号： US20240360154A1公开(公告)日： 2024-10-31
- 发明人: Fusheng ZHOU , Tao JIANG , Yingtao LIU , Chonglan LIN , Leitao ZHANG , Zhubo LIU , Kai MA , Wan HE , Xiaoming XU , Lijian FENG , Xiaoling LAN , Qian DING , Qiang LV , Jiong LAN
- 申请人： GENFLEET THERAPEUTICS (SHANGHAI) INC. , ZHEJIANG GENFLEET THERAPEUTICS CO., LTD.
- 申请人地址： CN Shanghai
- 专利权人： GENFLEET THERAPEUTICS (SHANGHAI) INC.,ZHEJIANG GENFLEET THERAPEUTICS CO., LTD.
- 当前专利权人： GENFLEET THERAPEUTICS (SHANGHAI) INC.,ZHEJIANG GENFLEET THERAPEUTICS CO., LTD.
- 当前专利权人地址： CN Shanghai
- 优先权： CN 2011009451.3 2020.09.23 CN 2110150660.8 2021.02.03 CN 2111038855.X 2021.09.06
- 国际申请： PCT/CN2021/119507 2021.09.21
- 进入国家日期： 2023-03-14
- 主分类号： C07D498/22
- IPC分类号： C07D498/22 ; A61K31/4985 ; A61K31/5386 ; A61P35/00 ; C07D471/14 ; C07D471/22 ; C07D491/22
摘要：
Disclosed are an aroyl substituted tricyclic compound, a preparation method therefor and use thereof. Specifically, the aroyl substituted tricyclic compound of the present invention has a structure of formula (C), and has, as a BTK inhibitor, the advantages of high activity, good selectivity and low toxic and side effects.
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