Invention Publication
- Patent Title: COMPOUNDS FOR PREVENTING, INHIBITING, OR TREATING CANCER, AIDS AND/OR PREMATURE AGING
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Application No.: US18435619Application Date: 2024-02-07
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Publication No.: US20240343716A1Publication Date: 2024-10-17
- Inventor: Jamal TAZI , Florence MAHUTEAU , Pierre ROUX , Romain NAJMAN , Didier SCHERRER , Carsten BROCK , Nathalie CAHUZAC , Gilles GADEA , Noelie CAMPOS , Aude GARCEL , Julien SANTO
- Applicant: ABIVAX , CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE , INSTITUT CURIE , UNIVERSITE DE MONTPELLIER
- Applicant Address: FR Paris
- Assignee: ABIVAX,CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE,INSTITUT CURIE,UNIVERSITE DE MONTPELLIER
- Current Assignee: ABIVAX,CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE,INSTITUT CURIE,UNIVERSITE DE MONTPELLIER
- Current Assignee Address: FR Paris; FR Paris; FR Paris; FR Montpellier
- Priority: EP 162630.9 2009.06.12 EP 305540.8 2009.06.12
- The original application number of the division: US16787471 2020.02.11
- Main IPC: C07D413/04
- IPC: C07D413/04 ; A61K31/4709 ; A61K31/4985 ; C07D213/74 ; C07D215/38 ; C07D215/42 ; C07D215/46 ; C07D217/02 ; C07D241/44 ; C07D401/12 ; C07D403/12

Abstract:
The manufacture and use of compounds of formula (Ia) or a pharmaceutically acceptable salt thereof for preventing, inhibiting or treating cancer, AIDS and/or premature aging. The compounds of formula (Ia) being:
where:
R independently represents a hydrogen atom, a halogen atom, a (C1-C3)alkyl group, a —CN group, a hydroxyl group, a —COOR1 group, a (C1-C3)fluoroalkyl group, a —NO2 group, a —NR1R2 group, or a (C1-C3)alkoxy group;
R′ is a hydrogen atom, a halogen atom, a (C1-C3)alkyl group, a —NO2 group, a (C1-C3)alkoxy group, or a —NR1R2 group; and
R1 and R2 are a hydrogen atom or a (C1-C3)alkyl group.
where:
R independently represents a hydrogen atom, a halogen atom, a (C1-C3)alkyl group, a —CN group, a hydroxyl group, a —COOR1 group, a (C1-C3)fluoroalkyl group, a —NO2 group, a —NR1R2 group, or a (C1-C3)alkoxy group;
R′ is a hydrogen atom, a halogen atom, a (C1-C3)alkyl group, a —NO2 group, a (C1-C3)alkoxy group, or a —NR1R2 group; and
R1 and R2 are a hydrogen atom or a (C1-C3)alkyl group.
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