- 专利标题： HYDROISOQUINOLINE OR HYDRONAPHTHYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE
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申请号： US18016289申请日： 2021-07-12
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公开(公告)号： US20240317735A1公开(公告)日： 2024-09-26
- 发明人: Fabian DEY , Xiaoqing WANG , Zhisen ZHANG , Wei ZHU
- 申请人： Hoffmann-La Roche Inc.
- 申请人地址： US NJ 8 - Legal Department Little Falls,
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ 8 - Legal Department Little Falls
- 优先权： WO TCN2020101904 2020.07.14 WO TCN2021094138 2021.05.17
- 国际申请： PCT/EP2021/069294 2021.07.12
- 进入国家日期： 2023-01-13
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/4375 ; A61K31/4545 ; A61K31/4725 ; A61K31/496 ; A61K31/4985 ; A61K31/4995 ; A61K31/5377 ; A61K31/5386 ; C07D519/00
摘要：
The present invention relates to compounds of formula (I),
wherein R1, R2, R3a, R3b, R4, Q, Z and Y are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
wherein R1, R2, R3a, R3b, R4, Q, Z and Y are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
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