Filling stations are provided that include a transfer tray having filling receptacles and a closing device arranged under the filling receptacles to open and close bottom openings in the filling receptacles, an optical detection device to generate images of filling receptacles having drug portions arranged therein, and a control device coupled to the optical detection device. The control device causes displaying of a filling template of which filling receptacles are to be filled with one or more drug portions, comparing an actual filling of the filling receptacles based on the one or more images of the filling receptacles generated by the optical detection device to a target filling, determining that no deviation exists between the actual filling and the target filling, and opening the closing device for transferring the drug portions from the transfer tray to a transport tray. Systems and methods for filling a transfer tray are also provided.