![4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS](/docs/US/2024-09-26/US20240316024A1/abs.jpg.600x600.jpg)
- 专利标题： 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS
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申请号： US18443907申请日： 2024-02-16
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公开(公告)号： US20240316024A1公开(公告)日： 2024-09-26
- 发明人: Lori Jean Patterson , Eric L. Strangeland , Sheila Zipfel , Daniel D. Long
- 申请人： THERAVANCE BIOPHARMA R&D IP, LLC
- 申请人地址： US CA South San Francisco
- 专利权人： THERAVANCE BIOPHARMA R&D IP, LLC
- 当前专利权人： THERAVANCE BIOPHARMA R&D IP, LLC
- 当前专利权人地址： US CA South San Francisco
- 分案原申请号： US14848933 2015.09.09
- 主分类号： A61K31/4465
- IPC分类号： A61K31/4465 ; C07D211/22 ; C07D211/32
![4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS](/abs-image/US/2024/09/26/US20240316024A1/abs.jpg.150x150.jpg)
摘要：
The invention relates to compounds of formula I:
where a, R1, and R3-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
where a, R1, and R3-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
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