Invention Publication
- Patent Title: TARGETED DEAMINASE AND BASE EDITING USING SAME
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Application No.: US18025446Application Date: 2021-09-17
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Publication No.: US20240294945A1Publication Date: 2024-09-05
- Inventor: Jin-Soo KIM , Kayeong LIM , Sung lk CHO , Beum-Chang KANG , Seonghyun LEE , Hyunji LEE , Young Geun MOK , Ji Min LEE , Eugene CHUNG
- Applicant: INSTITUTE FOR BASIC SCIENCE
- Applicant Address: KR Daejeon
- Assignee: INSTITUTE FOR BASIC SCIENCE
- Current Assignee: INSTITUTE FOR BASIC SCIENCE
- Current Assignee Address: KR Daejeon
- Priority: KR 20200120399 2020.09.18 KR 20200159920 2020.11.25 KR 20210013263 2021.01.29 KR 20210016788 2021.02.05 KR 20210049348 2021.04.15 KR 20210050497 2021.04.19 KR 20210085473 2021.06.30 KR 20210085474 2021.06.30 KR 20210092056 2021.07.14 KR 20210114750 2021.08.30
- International Application: PCT/KR2021/012872 2021.09.17
- Date entered country: 2023-03-09
- Main IPC: C12N15/90
- IPC: C12N15/90 ; A61K48/00 ; C12N9/22 ; C12N9/78 ; C12N15/10 ; C12N15/82
Abstract:
The present invention relates to a cytosine or adenine deaminase in an isolated form or a variant thereof, a non-toxic full-length cytosine deaminase or a variant thereof, a fusion protein comprising same, a composition for base editing, and a method for editing a base by using same.
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