A system for generating calibration data in an active antenna system (AAS) radio includes an array of directional couplers within a multi-channel transmit/receive signal path of the AAS radio, and a combiner network electrically coupled to the array of directional couplers. An array of filters is provided within the multi-channel transmit/receive signal path. The array of filters is electrically coupled to antenna-side terminals of the array of directional couplers. A plurality of pairs of transmitters and receivers are provided, which include a transmitter and a receiver that operate as a reference transmitter and a reference receiver, respectively. A removable routing network is provided, which is electrically coupled to antenna-side terminals of the array of filters, and is configured to feed back factory calibration signals (generated by the AAS radio during factory calibration) to antenna-side terminals of the array of filters. A multi-stage switch network is provided, which is electrically coupled to the reference transmitter, the reference receiver, the combiner network, and a factory calibration port of the routing network.