发明公开
- 专利标题： TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE
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申请号： US18555139申请日： 2022-04-12
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公开(公告)号： US20240246955A1公开(公告)日： 2024-07-25
- 发明人: Jing LIU , Jialiang WANG , Xiaoran HAN , Ting YANG
- 申请人： CULLGEN (SHANGHAI), INC.
- 申请人地址： CN Shanghai
- 专利权人： CULLGEN (SHANGHAI), INC.
- 当前专利权人： CULLGEN (SHANGHAI), INC.
- 当前专利权人地址： CN Shanghai
- 优先权： WO TCN2021086732 2021.04.21
- 国际申请： PCT/CN2022/086258 2022.04.12
- 进入国家日期： 2023-10-12
- 主分类号： C07D417/14
- IPC分类号： C07D417/14 ; A61K31/506 ; A61P35/00 ; C07D401/14 ; C07D403/14
摘要：
Heterobifunctional compounds (e.g., bi-functional small molecule compounds) and compositions comprising one or more of the heterobifunctional compounds are provided. The heterobifunctional compounds are used for the treatment of certain disease in a subject in need thereof. Methods for identifying such heterobifunctional compounds are also presented.
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