发明公开
- 专利标题： SUBSTITUTED PYRIDINE N-OXIDE DERIVATIVES USEFUL AS A FACTOR XIA INHIBITORS
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申请号： US18428046申请日： 2024-01-31
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公开(公告)号： US20240228465A1公开(公告)日： 2024-07-11
- 发明人: Guozhang Xu , Tho V. Thieu , Zhijie Liu , Micheal D. Gaul
- 申请人： Janssen Pharmaceutica NV
- 申请人地址： BE Beerse
- 专利权人： Janssen Pharmaceutica NV
- 当前专利权人： Janssen Pharmaceutica NV
- 当前专利权人地址： BE Beerse
- 主分类号： C07D401/14
- IPC分类号： C07D401/14
摘要：
The present invention provides imidazole substituted pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.
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