![2,8-DIAZASPIRO[4.5]DECANE COMPOUNDS](/docs/US/2024-05-30/US20240174696A1/abs.jpg.600x600.jpg)
- 专利标题： 2,8-DIAZASPIRO[4.5]DECANE COMPOUNDS
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申请号： US18526572申请日： 2023-12-01
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公开(公告)号： US20240174696A1公开(公告)日： 2024-05-30
- 发明人: Steven John MCKERRALL , Alice Rose WONG , James John CRAWFORD , Wendy LEE , Kwong Wah LAI , Guillaume PELLETIER , Stéphanie ROY , Dana Krystin WINTER , Mikiko OKUMURA , Ruth Dorel
- 申请人： Genentech, Inc.
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 优先权： WO TCN2021098358 2021.06.04
- 主分类号： C07D519/00
- IPC分类号： C07D519/00 ; A61P11/00
![2,8-DIAZASPIRO[4.5]DECANE COMPOUNDS](/abs-image/US/2024/05/30/US20240174696A1/abs.jpg.150x150.jpg)
摘要：
Disclosed are 2,8-diazaspiro[4.5]decane compounds, including (pyrido[3,4-d]pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane compounds, (2,6-naphthyridin-1-yl)-2,8-diazaspiro[4.5]decane compounds, and (1,7-naphthyridin-4-yl)-2,8-diazaspiro[4.5]decane compounds, that are inhibitors of LATS1/2, compositions containing these compounds, and methods for inhibiting LATS1/2 activity.
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