Methods, systems, and apparatus for supporting uplink Transmission Time Interval (TTI) bundling in Long Term Evolution (LTE) are provided. Methods, systems, and apparatus for signaling, activation/deactivation, and wireless transmit/receive unit (WTRU) behavior are also provided. In an example, a downlink control information (DCI) associated with a repeated physical uplink shared channel (PUSCH) transmission may be received. A hybrid acknowledgment repeat request (HARQ) process information may be determined using the received DCI. A repeated PUSCH transmission may be sent in accordance with one or more time units, the repetition configuration, and the HARQ process information.