A chemical reaction hazard analysis method is disclosed. Safety data and preventive measures of a chemical reaction are obtained through analysis of material stability, reaction process hazards and reaction runaway. The method can shorten a distance from laboratory to industrialization and realize an organic combination and application of technology, safety and engineer. The data obtain by the method can provide underlying basic data for process design, engineer amplification and the like, and lay a foundation for realizing process safety, improving quality and increasing efficiency.