Invention Application
- Patent Title: TEXAPHYRIN-PT(IV) CONJUGATES AND COMPOSITIONS FOR USE IN OVERCOMING PLATINUM RESISTANCE
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Application No.: US17807245Application Date: 2022-06-16
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Publication No.: US20230113036A1Publication Date: 2023-04-13
- Inventor: Jonathan L. SESSLER , Jonathan ARAMBULA , Zahid H. SIDDIK , Gregory THIABAUD
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Main IPC: A61K31/555
- IPC: A61K31/555 ; A61K47/54 ; A61K47/60 ; A61K49/08 ; A61K49/10 ; C07D487/22 ; C07F15/00
Abstract:
The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
Information query
