According to an aspect of the present invention, a terminal device transmits administration completion information to a support control apparatus together with unique identification information of the patient. The support control apparatus receives the administration completion information and stores it in association with the unique identification information, extracts a patient corresponding to an extraction condition as a research target person based on the administration completion information and a preset extraction condition, and transmits a request for response to the terminal device of the extracted research target person. The terminal device returns response information representing a condition after medicine administration input by the patient in response to the request for response to the support control apparatus together with the unique identification information. The support control apparatus estimates a condition change of the patient after the medicine administration based on the response information, and outputs the result.