- 专利标题: HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN
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申请号: US18137939申请日: 2023-04-21
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公开(公告)号: US20230373925A1公开(公告)日: 2023-11-23
- 发明人: Mark Thomas Miller , Dennis James Hurley , Timothy Donald Neubert , Vijayalaksmi Arumugam , Sara Sabina Hadida Ruah , Jason McCartney , Jinglan ZHOU , Jaclyn Chau , Robert Martin Demoret , Senait G. Ghirmai , Roman Askatovich Valiulin , Alexander Frederik Kintzer , David Robert Slochower , Kathleen Aertgeerts , Elizabeth Mary Beck , James Jun Bon Mui , Miranda Adele Wright , Ronald Marcellus Alphonsus Knegtel , Ewa Iwona Chudyk , Joanne Louise Pinder , James Dodd
- 申请人: VERTEX PHARMACEUTICALS INCORPORATED
- 申请人地址: US MA Boston
- 专利权人: VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人: VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人地址: US MA Boston
- 主分类号: C07D215/233
- IPC分类号: C07D215/233 ; C07D471/04 ; C07D239/91 ; C07D401/14 ; C07D401/04 ; C07D519/00
摘要:
Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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