A graphics processor can include a processing cluster array including a plurality of processing clusters coupled with the plurality of memory controllers, each processing cluster of the plurality of processing clusters including a plurality of streaming multiprocessors, the processing cluster array configured for partitioning into a plurality of partitions. The plurality of partitions include a first partition including a first plurality of streaming multiprocessors configured to perform operations for a first neural network, The operations for the first neural network are isolated to the first partition. The plurality of partitions also include a second partition including a second plurality of streaming multiprocessors configured to perform operations for a second neural network. The operations for the second neural network are isolated to the second partition and protected from operations performed for the first neural network.