Invention Publication
- Patent Title: MANUFACTURING PROCESS FOR HIGH TITER ANTIBODY
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Application No.: US18175852Application Date: 2023-02-28
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Publication No.: US20230331776A1Publication Date: 2023-10-19
- Inventor: John Mattila , Xiaolin Tang , Hanne Bak , Shawn M. Lawrence , Amy S. Johnson , Meghan Casey , Michelle LaFond , Andrew Tustian , Philip Mellors , John Hourihan , John Crowley , Laura Callinan , Shadia Abike Oshodi , Ashley Witmer , Daniel Corbett , James Reilly , Ankit Vartak , Mark Chiboroski , Alessandra Starling , Robert Stairs , Hai-Yuan Goh , Liam Nicholl , Aishling Conlon
- Applicant: Regeneron Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Main IPC: C07K1/36
- IPC: C07K1/36
Abstract:
The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.
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