- 专利标题： RECEPTORS PROVIDING TARGETED COSTIMULATION FOR ADOPTIVE CELL THERAPY
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申请号： US18157027申请日： 2023-01-19
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公开(公告)号： US20230227576A1公开(公告)日： 2023-07-20
- 发明人: John Bridgeman , Robert Hawkins , Ruben Rodriguez , Gray Kueberuwa , Milena Kalaitsidou , Michael Gavin King
- 申请人： Instil Bio (UK) Limited , Instil Bio, Inc.
- 申请人地址： GB TX Manchester
- 专利权人： Instil Bio (UK) Limited,Instil Bio, Inc.
- 当前专利权人： Instil Bio (UK) Limited,Instil Bio, Inc.
- 当前专利权人地址： GB TX Manchester
- 主分类号： C07K16/30
- IPC分类号： C07K16/30 ; C07K7/06 ; C07K14/715 ; C07K14/725 ; A61K35/17 ; C12N5/0783
摘要：
The present invention relates to a chimeric costimulatory antigen receptor (CoStAR) useful in adoptive cell therapy (ACT), and cells comprising the CoStAR. The CoStAR can act as a modulator of cellular activity enhancing responses to defined antigens. The present invention also provides CoStAR proteins, nucleic acids encoding the CoStAR and therapeutic uses thereof.
公开/授权文献
- US1728122A Television system 公开/授权日：1929-09-10
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