A system for programming an eFuse array in an integrated circuit (IC) includes an eFuse data file which has a first plurality of bits. The system includes a data compression module which has an input coupled to receive the eFuse data file. The data compression module reduces the size of the eFuse data file and provides a compressed data file. The compressed data file has fewer bits than the eFuse data file. The system includes an eFuse controller which has an input coupled to receive the compressed data file. The eFuse controller programs the eFuse array to permanently store the compressed data file in the eFuse array.