- 专利标题： DNA SEQUENCING USING HYDROGEL BEADS
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申请号： US17451771申请日： 2021-10-21
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公开(公告)号： US20220106588A1公开(公告)日： 2022-04-07
- 发明人: Yir-Shyuan Wu , Filiz Gorpe-Yasar , Tarun Kumar Khurana , Victoria Popic , Erich B. Jaeger , Mostafa Ronaghi
- 申请人： Illumina, Inc.
- 申请人地址： US CA San Diego
- 专利权人： Illumina, Inc.
- 当前专利权人： Illumina, Inc.
- 当前专利权人地址： US CA San Diego
- 主分类号： C12N15/10
- IPC分类号： C12N15/10 ; C12Q1/6806 ; B01L3/00 ; B01L7/00 ; C12Q1/6834
摘要：
Systems, methods, and compositions provided herein relate to preparation of beads encapsulating long DNA fragments for high-throughput spatial indexing. Some embodiments include preparation of nucleic acid libraries within the bead, wherein the bead includes pores that allow diffusion of reagents while retaining genetic material.
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