- 专利标题: ANTI-PD-L1 ANTIBODIES AND METHODS OF MAKING AND USING THEREOF
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申请号: US16615112申请日: 2018-06-22
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公开(公告)号: US20220002417A1公开(公告)日: 2022-01-06
- 发明人: Brian KOVACEVICH , Dong XIA , Anne E. JENSEN , Jonathan K. FALLEN , Blair RENSHAW , Jeffrey B. Adamo , Phil TAN , Zeren GAO , Yi ZHU
- 申请人: SYSTIMMUNE, INC. , SICHUAN BAILI PHARMACEUTICAL CO. LTD.
- 申请人地址: US WA Redmond; CN Chengdu
- 专利权人: SYSTIMMUNE, INC.,SICHUAN BAILI PHARMACEUTICAL CO. LTD.
- 当前专利权人: SYSTIMMUNE, INC.,SICHUAN BAILI PHARMACEUTICAL CO. LTD.
- 当前专利权人地址: US WA Redmond; CN Chengdu
- 国际申请: PCT/US2018/039144 WO 20180622
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K45/06 ; A61K39/395 ; A61P35/00
摘要:
The application provides the anti-PD-L1 monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.
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