- 专利标题: Anti-PD-L1 antibodies and methods of making and using thereof
-
申请号: US16615112申请日: 2018-06-22
-
公开(公告)号: US11560431B2公开(公告)日: 2023-01-24
- 发明人: Brian Kovacevich , Dong Xia , Anne E. Jensen , Jonathan K. Fallen , Blair Renshaw , Jeffrey B. Adamo , Phil Tan , Zeren Gao , Yi Zhu
- 申请人: SYSTIMMUNE, INC. , SICHUAN BAILI PHARMACEUTICAL CO. LTD.
- 申请人地址: US WA Redmond; CN Chengdu
- 专利权人: SYSTIMMUNE, INC.,SICHUAN BAILI PHARMACEUTICAL CO. LTD.
- 当前专利权人: SYSTIMMUNE, INC.,SICHUAN BAILI PHARMACEUTICAL CO. LTD.
- 当前专利权人地址: US WA Redmond; CN Chengdu
- 代理商 Zhihua Han
- 国际申请: PCT/US2018/039144 WO 20180622
- 国际公布: WO2019/005634 WO 20190103
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61P35/00 ; A61K39/395 ; A61K45/06
摘要:
The application provides the anti-PD-L1 monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.
公开/授权文献
信息查询