A single architected instruction to perform multiple functions is executed. The executing includes performing a first function of the multiple functions and a second function of the multiple functions. The first function includes moving a block of data from one location to another location, and the second function includes setting one portion of a storage key using one selected key and another portion of the storage key using another selected key. The storage key is associated with the block of data and controls access to the block of data. The first function and the second function are performed as part of the single architected instruction.